PSC is a rare liver disease estimated to affect 4,000+ Canadians

A diagnosis of primary sclerosing cholangitis can be overwhelming. PSC Partners Canada helps Canadians navigate living with this progressive disease by providing information, support, and hope.

The mission of PSC Partners Seeking a Cure Canada is to drive research to identify treatments and a cure for PSC, while providing education and support for those impacted by this rare disease.

Research

Finding treatments for PSC

Funding

Raising funds for PSC research

Resources

Sharing Canadian-specific & PSC-related resources

Support

Helping individuals throughout their PSC journey

Awareness

Encouraging & facilitating conversations about PSC

Helping Canadians Navigate Living with PSC

Initial Diagnosis

Newly diagnosed with PSC? PSC Partners Canada provides resources and support to help understand this disease. Disease progression is different for each person, but it helps to know the basic facts.

Living with PSC

Connecting with support groups and learning more about the condition can help manage the emotional and physical challenges of living with a chronic illness.

Advancing PSC

As PSC advances, more serious complications can occur. Understanding, monitoring, and managing the signs of advanced PSC with your medical care team is crucial for timely intervention and medical care.

Liver Transplant

Not all patients diagnosed with primary sclerosing cholangitis will need a liver transplant. For those who do, it can be a chance for an improved quality of life. Many liver transplant patients notice positive changes just hours after surgery.

Caregivers and Family

Caregivers and family are an essential support system for those living with PSC. Ideally, supporting someone with PSC involves balancing your own well-being while managing PSC-related challenges.

Research and Information

In addition to driving research for treatments and a cure for PSC, PSC Partners Canada actively works to connect those affected by PSC with cutting-edge research and clinical trials.

PSC Partners Annual Conference 2025: Save the Date!

Calendar Friday, September 12, 2025

Denver, Colorado

Mark your calendars and pack your bags for a weekend filled with connection, education, and empowerment. Denver’s breathtaking scenery, vibrant culture, and welcoming community make it the perfect backdrop for this can’t-miss event.

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Edmonton – What the Cell?! On Tour: A Canadian PSC Patient Event

Calendar Saturday, October 4, 2025

Edmonton, AB

10:00 am - 4:00 pm MDT

2025 Edmonton PSC patient & caregiver event. Learn about PSC & promising PSC research. Enjoy lunch & opportunities for peer support and community building. Advanced registration required.

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The Loon Duct – PSC Partners Canada’s quarterly newsletter

PSC Partners Canada’s newsletter “The Loon Duct” provides updates on initiatives, research, events, and other information impacting the PSC community in Canada.

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Funding for Canadian collaborative PSC research team announced

Canadian non-profit Conscience announces a PSC project that has been approved for its Developing Medicines through Open Science (DMOS) program. The DMOS program PSC grantees are working towards treatments and cures for PSC.

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View all news and events

PSC Stories

Explore the personal journeys of individuals living with PSC and find inspiration in their stories. Connect with those who truly understand PSC and gain valuable insights from their experiences. Discover a community offering hope, guidance, and encouragement. Each story is unique, offering new perspectives and shared strength.

Jackson – Using Sports and Competition to Cope with PSC

Jackson Blizzard, a 25-year-old weightlifter and former motocross racer, shares his journey with primary sclerosing cholangitis (PSC). Diagnosed at 19, Jackson continues to train and compete, finding strength through motivation...

Sandra Holdworth, a liver transplant recipient

Sandra – Lessons learned from 25 years post-liver transplant

Diagnosed with PSC in 1995, Sandra Holdsworth shares her experience of living with PSC and IBC, as well as having a liver transplant. Looking back, Sandra offers tips for coping...

Andy – From Fear to Hope

When Andy was diagnosed with PSC, like many others, he was overwhelmed by the realities of this disease. He was left feeling scared, anxious, and alone. Andy took a step...

Jillian – Advocacy and Active Living Post-Transplant

Jillian had a life saving liver transplant in 2016. Two months after her transplant she hit the gym and pool to start training. She competed at the World Transplant Games...

Jessica – From Diagnosis to Determination

After being diagnosed with ulcerative colitis in 2003, Jessica was also diagnosed with PSC a year later. She has fought through 2 emergency surgeries and has a liver transplant on...

Richard Ayuen, a PSC Canada Board member, and son

Richard – Being a PSC caregiver and liver donor to his son

Richard Ayuen talks about his experiences as a caregiver to his son with PSC, donating part of his liver and his involvement with PSC Partners Canada.

Volunteer

Make a difference with PSC Partners Canada—whether by mentoring, helping at events, writing, or fundraising, every volunteer role strengthens and supports the PSC community.

Volunteer

Donate

Donations fuel PSC Partners Canada’s mission to drive research toward treatments and a cure. Together, a brighter future can be created for everyone impacted by PSC.

Donate

Patient Registry

By contributing health information to the PSC Patient Registry, participants help researchers better understand PSC. More data can accelerate progress toward effective treatments and a cure.

Support

PSC Partners Canada offers a community where people can share experiences, find advice, and connect with others who truly understand the challenges of living with PSC.

Support